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Aug 17, 2019

Function from structure: the double life of a DUB

Deubiquitinases (DUBs) play a general role removing protein-degrading ubiquitins throughout the cell and are not typically known for specificity. Analyzing the two protein complexes BRISC and BRCA1-A, which have the same DUB core but play different roles in human biology, the Thomä group - in a collaboration with the Novartis Institutes for BioMedical Research (NIBR) - showed that DUBs can have diversified targeting and regulatory functions. Read more

Aug 05, 2019

Unlocking the secrets of an important regulator of human development

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Jul 21, 2019

Friedrich Miescher – 150 years of DNA

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Jun 24, 2019

In conversation with our two new group leaders

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Next seminars & events

Aug 22, 2019. Time: 11:30  FMI Room 530  Add to my calendar  Register for this event

Neural mechanism of bodily self-consciousness
Olaf Blanke, EPFL, Lausanne

Aug 29, 2019. Time: 12:15  FMI Room 530  Add to my calendar  Register for this event

Joint molecules of homologous recombination: friends and foes of genomic stability
Aurele Piazza, Institut Pasteur, Paris, France

Sep 09, 2019. Time: 15:30  FMI Room 530  Add to my calendar  Register for this event

Take the Bull by the Horns: What you can do to take steps to a fulfilling career in science
Joanne Kamens, Executive Director, Addgene, Watertown, MA, USA
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Sep 24, 2019. Time: 15:00  FMI Room 530  Add to my calendar  Register for this event

The structure of the nuclear pore complex - an update
André Hoelz, Caltech, Pasadena, CA, USA

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Recent Publications

Voigt F, Eglinger J, Chao JA Quantification of mRNA Turnover in Living Cells: A Pipeline for TREAT Data Analysis. Methods Mol Biol. 2019;2038:75-88

Tiana G, Giorgetti L Coarse Graining of a Giant Molecular System: The Chromatin Fiber. Methods Mol Biol. 2019;2022:399-411

Welte T, Tuck AC, Papasaikas P, Carl SH, Flemr M, Knuckles P, Rankova A, Bühler M, Großhans H The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1. Genes Dev. 2019 Aug 1

Jüttner J, Szabo A, Gross-Scherf B, Morikawa RK, Rompani SB, Hantz P, Szikra T, Esposti F, Cowan CS, Bharioke A, Patino-Alvarez CP, Keles Ö, Kusnyerik A, Azoulay T, Hartl D, Krebs AR, Schübeler D, Hajdu RI, Lukats A, Nemeth J, Nagy ZZ, Wu KC, Wu RH, Xiang L, Fang XL, Jin ZB, Goldblum D, Hasler PW, Scholl HPN, Krol J, Roska B Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans. Nat Neurosci. 2019 Aug;22(8):1345-1356

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Group leaders Videos

TED talk by Nico Thomä (May 11, 2019 - Basel)

Prisca Liberali (Quantitative Biology)
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